Israel carried out airstrikes on a defunct military air base in northwestern Syria on Tuesday, prompting the United States to condemn the attack as a threat to regional stability in the latest outburst of American frustration with Israel.

Syrian and American officials said Israel carried out the attack, while the Israeli military declined to comment. Eight airstrikes hit the Abu al-Duhur military air base in Idlib, a city in the northwest about 40 miles from the border with Turkey, according to Syrian state media, and did not cause any casualties.

The Trump administration has been a vocal proponent of Syria’s new government led by President Ahmed al-Sharaa, and the U.S. special envoy to Syria and Iraq, Tom Barrack, said in a statement on social media that Israel’s actions “constitute an unnecessary escalation.”

“The Al-Sharra government has neither adopted a predatory posture nor maintained proxy forces,” he added. “It has, in fact, repeatedly indicated a preference for de-escalation with Israel.”

Mr. Barrack’s comments followed a series of fractures between Israel and the United States in recent weeks.

Prime Minister Benjamin Netanyahu of Israel this month rejected a U.S.-backed deal for Hamas to disarm in an unusually public break with President Trump. Jared Kushner, Mr. Trump’s son-in-law and a senior aide, held talks with Mr. Netanyahu about the deal on Monday but with no indication of progress.

Last week, the U.S. ambassador to Israel, Mike Huckabee, condemned Israeli settlers in the West Bank who had besieged two Palestinian families in their homes, one of which is owned by a Palestinian American. Mr. Huckabee, a longtime supporter of the settler movement, called the actions a “horrific act of terror,” and said the United States had urged Israel to intervene.

The Syrian base has been out of service since 2013, and control of the facility changed hands several times during the nearly 14-year civil war between the government of Bashar al-Assad and rebel forces.

The Israeli strikes are part of a broader pattern of military activity in Syria since rebels led by Mr. al-Shara swept into the capital, Damascus, in 2024 and overthrew Mr. al-Assad.

Since seizing power, Syria’s new government has rapidly consolidated authority across the country, bringing relative calm after a brutal civil war. Still, that calm remains fragile, punctuated by sporadic attacks from Islamic State and other extremist groups, as well as sectarian tensions that erupted into violence twice last year.

The Israeli military has launched hundreds of airstrikes on military targets across the country and deployed forces deep into parts of southern Syria near its border with Israel since Mr. Assad was ousted. Israeli forces have also built nine new military outposts as well as supporting infrastructure like military roads and electricity networks in southern Syria, according to the Armed Conflict Location and Event Data, or A.C.L.E.D., a nonprofit organization that tracks global conflict.

The Israeli military’s actions have stoked fears in Syria that Israel is seeking to maintain a long-term military presence in the country, and may expand its operations beyond the southern border areas.

Israeli officials have defended the actions as necessary to ensure that hostile forces such as the Iranian-backed Lebanese militant group, Hezbollah, or the Islamic State, cannot entrench themselves in Syrian territory.

It was not immediately clear why Israel targeted the base in Idlib, a city that was once the heartland of the rebel coalition that ousted the Assad government.

Two Syrian government officials, speaking on the condition of anonymity because they were not authorized to speak to the news media, said the strikes followed a recent visit by a Turkish delegation to the airfield as part of discussions to rehabilitate it.

Turkey is a key ally of the Syrian government. But Turkey’s relationship with Israel has deteriorated following the devastating war in Gaza as well as Israel’s interventions in Syria. Last year, Israel struck two air bases in Syria’s Homs Province after Turkish delegations had inspected them for possible use.

Turkish officials have not commented on the strikes.

The Syrian government condemned the attacks, saying that it considered them “an unjustified act of aggression, a flagrant violation of Syria’s sovereignty and territorial integrity, and a dangerous escalation that threatens security and stability in the region.”