The Beverly Hills property where Sharon Tate and four others were slain by sick-minded Manson family butchers has listed for $45 million, The Post has learned.

Jeff Franklin, the famed producer behind the iconic ’90s TV series “Full House,” has struggled for years to part ways with the Mediterranean-style hillside mansion, built on top of the torn-down house where the murders occurred.

Striking in its new iteration, its amenities include a massive 225-foot swimming pool that can fit the Leaning Tower of Pisa — with enough room left for laps. 

Still, the Cielo Drive property — most recently asking $50 million — will likely never shake the haunting legacy of what happened almost 60 years ago in August 1969.

That’s when several of Charles Manson’s carnage-craving flunkies cut a path across the 3.6-acre grounds and killed Tate, who was eight months pregnant, and her hairstylist friend Jay Sebring in the home’s living room.

They also murdered her guests, the coffee heiress Abigale Folger and her boyfriend Wojciech Frykowski, where the pool now stands, and Steven Parent in an onsite guardhouse.

Efforts to thwart true-crime tourists who still come, some of whom leave strange offerings, have taken several forms over the years — including petitioning the city to change the site’s address, which was an easy lookup for people wanting a view.

Franklin, who now lives in Miami, purchased the property for $6.4 million in January 2000.

Hollywood talent manager Rudolph Altobelli was renting the place to Tate and her husband Roman Polanski at the time of the murders. 

What followed, while not as heinous as the murders, did show a dark side of Altobelli and others.

Altobelli moved back into the place three weeks after the killings and then made a move that sickened still-mourning Hollywood. He sued Polanski for breaking the one-year lease on the property when the director moved out after the murders and also billed him for the cleanup costs.

Tate and Polanski lived in the home for less than 6 months, paying $1,200 a month, or roughly $11,000 in today’s dollars. 

Years later, Nine Inch Nails frontman Trent Reznor rented the original home and installed a recording studio within. He named the studio “Le Pig,” after the infamous word that Manson’s followers scrawled on the front door in Sharon Tate’s blood.

Reznor took the now-sanded and repainted door with him when he left. But not before Reznor’s now-former friend, the goth shock-rocker Marilyn Manson, who had already taken his stage name from Marilyn Monroe and Charles Manson, recorded there and appeared in Nine Inch Nails’ video for “Gave Up,” which was filmed at this home.

Franklin is listing the estate after trying unsuccessfully to rent it for a colossal $247,500 a month — and it’s a far cry from its 2,300-square-foot, farmhouse-style predecessor. 

Within its 21,000 square feet are nine bedrooms, 12 full bathrooms and four half baths. A massive grand foyer entrance opens to 40-foot ceilings and a winding staircase below a dome ceiling and a fountain.

The main bedroom stands in a separate wing and has large dressing rooms, private terraces, a fireplace and spa-styled bathrooms that provide views of Beverly Hills.

There’s also an area that’s home to several sharks, though not as large as the “Jaws” kind. They reside in a 20-foot-long floor-to-ceiling saltwater aquarium that sits between the living room and the dining room. There are several large fish tanks in addition to the sharks’ and a multi-tiered projection room with a stage for performances. 

An infrared sauna is part of a beauty salon, and an entertainment area features an arcade room with video games and a photo booth, all surrounded by rich wood-paneled walls and ceilings.

The outside is like a water park, featuring a lagoon-style infinity pool amid three cascading waterfalls. A private river with a current allows residents and guests to float around the property’s grounds. And a 35-foot-long water slide leads to a grotto where guests can watch giant koi fish underwater through reinforced glass.

The property wasn’t always associated with tragedy.

Originally built in 1941, it had a Hollywood patina, with film pioneer Lillian Gish renting there and even the Baron Philippe de Rothschild leasing it when he was in town.

Henry Fonda hid out there from fans during the peak of his popularity. And iconic leading man Cary Grant used the property as a honeymoon nest when he married actress Diane Cannon.

Bennett Bidwell and Adam Rosenfeld of the Resident Group have the listing.