Dolly Parton, the country singer, songwriter, entertainer and entrepreneur whose rags-to-riches story, outsize persona and prodigious vision and talent placed her in a class by herself, died on Tuesday in Nashville. She was 80.

The death was announced in a video posted on social media by her nephew, Bryan Seaver. No cause was provided. Concerns about Ms. Parton’s health, which began last year as she postponed and later canceled a Las Vegas residency, grew to the point that she took to social media last fall to confirm that “I ain’t dead yet.” In May, she said she had responded well to treatment after, as she put it, her immune and digestive systems “got all out of whack” in recent years.

Ms. Parton’s life, as depicted in autobiographical songs like “Coat of Many Colors” and “My Tennessee Mountain Home,” was the stuff of make-believe, from her hardscrabble beginnings in Appalachia to her glittering stardom in Nashville and beyond.

The writer Chet Flippo likened her to the Big Rock Candy Mountain, the Depression-era symbol of abundance personified by Ms. Parton’s voluptuous figure, rhinestone-studded stage costumes and blonde bouffant wigs. Her songs spoke to millions, confronting privation and loss even as they radiated possibility and hope.

She was, quintessentially, a uniter of people. In 2019, The New York Times ran a story with the headline “Is There Anything We Can All Agree On? Yes: Dolly Parton.”

Ms. Parton cannily exploited — and transcended — rural stereotypes and kitsch to fashion a down-home chic entirely her own. (“A country girl’s idea of glam,” she called it in the song “Backwoods Barbie.”) In the process, she became an international celebrity who headlined stadium tours, starred in Hollywood movies, built a business empire and appeared on the cover of Rolling Stone. Her at times girlish soprano notwithstanding, she was anything but the “dumb blonde” invoked in the title of her 1966 single.

“I’ve created this and played it up — the makeup, the whole persona,” Ms. Parton said, alluding to her plastic surgeries as well as her colloquial “Dollyisms” in a 2002 interview with The Times.

“But this isn’t all I am,” she added. “It’s not even most of what I am. Hopefully people can see beneath the hair to know there’s a brain, beneath the boobs to know there’s a heart and behind all the other stuff to know there’s some talent.”

Inducted into both the country music and rock ’n’ roll halls of fame, Ms. Parton was the top-ranking female singer on country radio from 1967 to 1993, and had a total of 25 No. 1 country singles.

Her early breakthrough came in 1967 when she was hired as the “girl singer” on “The Porter Wagoner Show,” a syndicated country music television variety program. Several years later, she had No. 1 country hits with records like “Jolene” and “I Will Always Love You.”

Both songs were among about 3,000 titles she published in her lifetime, hundreds of which have been recorded by other artists, including Tina Turner, Norah Jones, the White Stripes, Merle Haggard, RuPaul and Whitney Houston.

Featured in the 1992 movie “The Bodyguard,” Ms. Houston’s version of “I Will Always Love You” spent 14 weeks at the top of the pop chart. The song had previously been a No. 1 country single twice, in versions released by Ms. Parton in 1974 and 1982.

With Loretta Lynn and Tammy Wynette, Ms. Parton blazed a trail for women in country music, inspiring contemporaries like Linda Ronstadt and Emmylou Harris, as well as latter-day hitmakers like Carrie Underwood, Kacey Musgraves and Taylor Swift. She recorded a pair of albums, “Trio” and “Trio II,” with Ms. Ronstadt and Ms. Harris.

“I can’t imagine anybody, especially in country, who doesn’t try to emulate Dolly in some way,” Ms. Harris said on the occasion of Ms. Parton’s Kennedy Center Honors in 2006.

Ms. Parton was one of country music’s greatest ambassadors, but she also collaborated widely with artists outside traditional Nashville circles, including Mavis Staples, Queen Latifah, Julio Iglesias and Ladysmith Black Mambazo. “Islands in the Stream,” a triple platinum-selling duet Ms. Parton recorded with Kenny Rogers, topped both the country and pop charts in 1983. (The song was written by Barry, Maurice and Robin Gibb of the Bee Gees.)

Stylistically, Ms. Parton’s music ran the gamut: mountain bluegrass and soul-inflected countrypolitan, disco-era pop and covers of classic rock touchstones written by Neil Young and Led Zeppelin — all of it rendered indelible by her irrepressible spirit and alternately keening and gossamer soprano drawl.

She wrote unabashedly, in simple Southern vernacular, about growing up as the daughter of an illiterate sharecropper.

“I’ve seen Daddy’s hands break open and bleed / And I’ve seen him work ’til he’s stiff as a board,” she sang over wistful harmonica and acoustic guitar in “In the Good Old Days (When Times Were Bad).” “I’ve seen Mama layin’ in sufferin’ and sickness / In need of a doctor we couldn’t afford. / Anything at all was more than we had / In the good old days when times were bad.”

In “Coat of Many Colors,” maybe her most beloved original, Ms. Parton plumbed childhood feelings of pride and humiliation. In this case, the coat in question — quilted from rags and originally a source of delight and the expression of a mother’s love — becomes an object of ridicule when Dolly’s classmates poke fun at her for wearing it to school.

So with patches on my britches

And holes in both my shoes,

In my coat of many colors

I hurried off to school

Just to find the others laughing

And making fun of me

In my coat of many colors

My Mama made for me

“That little song is like a world of things,” Ms. Parton said of “Coat of Many Colors” in “Dolly Parton, Songteller: My Life in Lyrics” (2020), written with Robert K. Oermann. “It teaches about bullying, about love, about acceptance, about good parents. That little story has even been written into a schoolbook to teach children about being different.”

Empathy was a hallmark of Ms. Parton’s songwriting, perhaps nowhere so much as in “Down From Dover” and “Daddy Come Get Me,” harrowing Southern gothic ballads about teen pregnancy and how patriarchy blames and victimizes young women.

Assertive women populated Ms. Parton’s songs, whether through her proto-feminist rewrite of Jimmie Rodgers’s “Mule Skinner Blues (Blue Yodel No. 8)” or by advocating parity in the bedroom (“Touch Your Woman”) and in the workplace (“9 to 5”).

“It’s a rich man’s game / No matter what they call it / And you spend your life / Putting money in his wallet,” Ms. Parton sang, with a mixture of fury and resolve, in the 1980 pink-collar comedy “9 to 5.” Besides writing and performing the movie’s theme song, a No. 1 pop and country hit, she also starred in the film as a beleaguered secretary drudging for a sexist boss, alongside Jane Fonda and Lily Tomlin.

Ms. Parton would go on to star in other films, among them “The Best Little Whorehouse in Texas” (1982), with Burt Reynolds; “Steel Magnolias” (1989), with Julia Roberts and Shirley MacLaine; and “Straight Talk” (1992), with James Woods.

In 1976, she became the first woman in country music to host her own syndicated TV series; a decade later, she had an hourlong variety show on ABC. But for all her reach and command as an entertainer — including her ubiquitous appearances on TV talk shows and specials — Ms. Parton viewed herself, first and foremost, as a songwriter.

“Writing’s just as natural to me as getting up and cooking breakfast,” she told The Times in 2002. “I ain’t never far away from a pencil and paper or a tape recorder. I write every day, even when I’m on a plane, in the tub or on the bus. It burns in me.”

She continued: “Songwriting is my way of channeling my feelings and my thoughts. Not just mine, but the things I see, the people I care about. My head would explode if I didn’t get some of that stuff out. Not everything I write is good, but it’s all good for me — like therapy.”

Dolly Rebecca Parton was born on Jan. 19, 1946, the fourth of 12 children of Robert Lee and Avie Lee (Owens) Parton, in a one-room cabin on the banks of the Little Pigeon River in Sevier County, Tenn. Her father was a tenant farmer, and her mother was a homemaker who sang old Anglo-Celtic ballads and hymns while doing housework.

The Partons were so poor that Dolly’s father had to pay the doctor who attended her birth with a sack of cornmeal. Ms. Parton may have grown up without plumbing, heat, electricity and other modern conveniences, but she always insisted that she also grew up happy, and that music offered her a refuge from want.

“Most of us in the household learned to play early on,” she said in “Dolly Parton, Songteller.” “Every time anybody showed up, any uncle or aunt who knew how to play an instrument, I’d have them show me how to play a little bit on the banjo, the guitar, the autoharp or whatever instrument was around.”

When she was 5 or so, she wrote her first song, a ditty about a corncob doll with corn-silk hair called “Little Tiny Tasseltop.” She started singing on radio and on TV at 10, on the “Cas Walker Farm and Home Hour” in Knoxville, securing bookings with the help of her uncle Bill Owens, who also bought her her first guitar. The two would go on to write many songs together.

Ms. Parton made her recording debut in 1959, the same year she made her first appearance at the Grand Ole Opry. In 1962, she signed a songwriting deal with Tree International Publishing (now part of Sony Music Publishing). Two years later, she became the first person in her family to graduate from high school.

In 1966, Ms. Parton married Carl Dean, an asphalt contractor who shunned the limelight. The couple had met two years earlier, at a laundromat in Nashville, when Ms. Parton was 18. Mr. Dean died in 2025.

Ms. Parton is survived by six of her siblings: Willadeene Parton, Robert Lee Parton Jr., Stella Parton, Cassie Parton, Freida Parton and Rachel Ann Parton George.

In 1965, Ms. Parton signed a recording contract with Monument Records, not long before she and her uncle wrote two Top 10 country songs for the singer Bill Phillips. She released the first of her roughly 90 Top 40 country hits — “Dumb Blonde,” a plucky denunciation of female stereotypes — in 1966.

In 1967, she began her seven-year tenure with “The Porter Wagoner Show.” She and Mr. Wagoner would go on to release 21 hit duets together, including “Holding On to Nothin’” (1968) and “Just Someone I Used to Know” (1969).

But with the arrival of the 1970s — and in no small part because of the national exposure she received on Mr. Wagoner’s show — Ms. Parton started to eclipse her employer in popularity.

The tension that resulted was further aggravated when she began steadily producing No. 1 country singles like “Joshua” and “Jolene.” Ms. Parton parted ways with Mr. Wagoner in 1974 to concentrate on her solo career, but not before writing “I Will Always Love You” as an expression of gratitude and farewell.

The separation initially proved difficult for Ms. Parton, both emotionally and financially, but it also opened doors to new opportunities like the chance to host her own TV show. She was named female artist of the year by the Country Music Association in each of the two years (1975 and 1976) after her break with Mr. Wagoner.

Embracing a more pop approach than she had earlier in her career, Ms. Parton continued her ascendance on the charts in the late ’70s with blockbuster hits like “Here You Come Again” and “Heartbreaker.” Both were No. 1 country singles that crossed over to the pop Top 40. The Country Music Association awarded her its top honor, entertainer of the year, in 1978.

After her 1980 recording of “9 to 5” earned her two Grammy Awards and an Oscar nomination, Ms. Parton turned her attention to movies, TV appearances and the development, in the mid-1980s, of Dollywood, her Smoky Mountain theme park, among other business ventures.

In 1987, she released the first of her two albums with Ms. Ronstadt and Ms. Harris, the platinum-selling “Trio.” She hosted “Saturday Night Live” in 1989 and teamed up with Ms. Lynn and Ms. Wynette to record the album “Honky Tonk Angels” in 1993.

She published her memoir, “Dolly: My Life and Other Unfinished Business,” a New York Times best seller, in 1994. The next year, she established the Imagination Library, a philanthropic endeavor through which more than 200 million books have been distributed to babies and young children.

Endowed with a surfeit of creativity and an unflagging work ethic, Ms. Parton admitted in interviews to sleeping as few as three hours a night. She was nominated for more than 50 Grammy Awards, 10 of which she won, along with being recognized for lifetime achievement by the Recording Academy in 2011.

Ms. Parton was inducted into the Country Music Hall of Fame in 1999 and the Songwriters Hall of Fame in 2001, and was awarded the National Medal of Arts in 2005. In 2022, she was inducted into the Rock & Roll Hall of Fame.

But perhaps even more remarkable than the profusion of accolades and awards was Ms. Parton’s unstinting generosity of spirit — her commitment, born of deep religious convictions and an immense heart, to seeing the humanity in all people.

Ms. Parton not only sang the traditional Southern gospel music her mother taught her; she also wrote and sang “Travelin’ Thru,” an Oscar-nominated song from “Transamerica,” the 2005 movie about a transgender woman seeking to connect with her son. In 2017, Ms. Parton collaborated with Miley Cyrus, her goddaughter, to record “Rainbowland,” a tribute to gay pride and liberation.

“You have to accept everything and everybody,” she said in “Songteller,” talking about the lessons to be learned about open-mindedness and inclusion from “Coat of Many Colors.”

Time and again in her career, Ms. Parton reflected on her impoverished upbringing and how she followed her dreams to escape it. “I wanted to be free,” she told Rolling Stone in 1977. “I had my songs to sing, I had an ambition, and it burned inside me.”

She added: “It was something I knew would take me out of the mountains. I knew I could see worlds beyond the Smoky Mountains.”