Joe Manganiello shares rare glimpse at mystery illness battle with heartbreaking hospital pics

Joe Manganiello shared a glimpse of his battle with a mystery illness by sharing heartbreaking photos of himself in the hospital.

“TRIGGER WARNING. In the days following the amputation of my large intestine, my weight began to plummet,” he captioned the carousel of images on Instagram Thursday.

“I would ultimately lose a total of 60 lbs during the two weeks following the surgery,” the “Magic Mike” star added.

“If you zoom in, you can see the top of my first ostomy bag creeping up over the sheets,” he claimed, referring to the photo of him sitting shirtless in a hospital chair.

Joe Manganiello shared images of himself in the hospital when he was battling a mystery illness. Instagram/@joemanganiello
The “Spider-Man” star (seen above with a rash on his face) said he lost 60 pounds after he had to have his large intestine amputated. Instagram/@joemanganiello

Manganiello, 49, then described the second photo, which shows a close-up of his “abdomen after the reconnection/take down surgery or anastomosis, in which my ostomy bag was removed and what was left of my digestive tract was reconnected.”

The “Spider-Man” actor said the third snap showed the “multitude of skin conditions I was plagued with during the seven years I was sick.”

“My skin, an immune organ, was stricken with just about every condition known to man, usually in combination,” he wrote of the images, which showed red rashes all over his face.

Manganiello first revealed he was battling a seven-year illness in the synopsis of his new memoir, “Bloodlines,” over the summer.

Manganiello (seen above on SiriusXM in October) said he also had a “multitude of skin conditions I was plagued with during the seven years I was sick.” SiriusXM
In his new memoir, Manganiello claimed his then-wife, Sofïa Vergara (seen above with the actor at a festival in 2019), ridiculed him when he was sick. Getty Images for Maui Film Festival

The “True Blood” alum said doctors could not explain the sickness that attacked his thyroid, digestive system, skin, lungs and eyes.

Instead, Manganiello said he used shamans, pagan rituals, ancient myths, long-lost family records and the rebirth of his own spirituality to try to aid his illness.

In his book, the actor revealed a shaman suggested that one of his then-wife Sofïa Vergara’s exes put a “voodoo curse” on him that caused the illness.

“‘Someone from your past is still in love with you. He put a voodoo curse on your husband. He did it in New Orleans,” he recalled the shaman telling him and the “Griselda” actress.

The “True Blood” alum said the illness sickness that attacked his thyroid, digestive system, skin, lungs and eyes. sofiavergara/Instagram
Manganiello and the “America’s Got Talent” judge (both seen above at the 2015 Screen Actors Guild Awards) split in 2023 after seven years of marriage. WireImage

Manganiello said he believed the person of interest was Vergara’s ex Nick Loeb, who previously lived in New Orleans.

In an exclusive statement to Page Six, Loeb, 51, said: “I pray they find Jesus — not another shaman.”

Manganiello also claimed Vergara, 54, ridiculed him when he was dealing with his illness. He also claimed that she refused to hug him when he was severely sick.

The author and the “America’s Got Talent” judge were married for seven years before they split in 2023.

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